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Lonigutamab - Pierre Fabre/ACELYRIN

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Drug Profile

Lonigutamab - Pierre Fabre/ACELYRIN

Alternative Names: anti-IGF-1R monoclonal antibody - ACELYRIN; VB-421

Latest Information Update: 22 Aug 2024

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At a glance

  • Originator Pierre Fabre
  • Developer ACELYRIN
  • Class Anti-inflammatories; Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action IGF type 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Graves ophthalmopathy
  • Preclinical Inflammation

Most Recent Events

  • 13 Aug 2024 ACELYRIN plans to hold an End-of-phase II meeting with the US FDA in 2024
  • 13 Aug 2024 ACELYRIN plans a phase III trial for Graves ophthalmopathy in the first half of 2025
  • 25 Mar 2024 ACELYRIN has patent protection for Lonigutamab in USA

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