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Zavondemstat - Tachyon Therapeutics

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Drug Profile

Zavondemstat - Tachyon Therapeutics

Alternative Names: QC-8222; TACH-101

Latest Information Update: 18 Sep 2025

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Tachyon Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Histone demethylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Haematological malignancies

Most Recent Events

  • 30 May 2025 Pharmacokinetics, efficacy and adverse events data from a phase I trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 18 Sep 2024 Pharmacodynamics data from preclinical trials in Solid tumours presented at the 40th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS-2024)
  • 05 Apr 2023 Preclinical trials in Haematological malignancies in USA (PO) as of April 2023 (Tachyon Therapeutics pipeline, April 2023)

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