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SC 291

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Drug Profile

SC 291

Alternative Names: SC-291

Latest Information Update: 25 Nov 2025

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At a glance

  • Originator Sana Biotechnology
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Autoimmune disorders

Highest Development Phases

  • Suspended Anti-neutrophil cytoplasmic antibody-associated vasculitis; Chronic lymphocytic leukaemia; Chronic myeloid leukaemia; Granulomatosis with polyangiitis; Lupus nephritis; Microscopic polyangiitis; Non-Hodgkin's lymphoma; Systemic lupus erythematosus

Most Recent Events

  • 07 Nov 2025 Suspended - Phase-I for Anti-neutrophil cytoplasmic antibody-associated vasculitis (Treatment-experienced) in USA (Parenteral)
  • 07 Nov 2025 Suspended - Phase-I for Granulomatosis with polyangiitis (Treatment-experienced) in USA (Parenteral)
  • 07 Nov 2025 Suspended - Phase-I for Lupus nephritis (Treatment-experienced) in USA (Parenteral)

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