CDX 585
Alternative Names: BSI-585; CDX-585; ILT4/PD-L1 bispecific antibody - Biosion/Celldex TherapeuticsLatest Information Update: 18 Mar 2024
At a glance
- Originator Biosion; Celldex Therapeutics Inc
- Developer Celldex Therapeutics Inc
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; LILRB2 protein inhibitors; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 31 Dec 2023 Celldex Therapeutics has patents pending for CDX 585 worldwide
- 14 Apr 2023 Pharmacodynamics and safety data from a preclinical studies in Solid tumours presented at the 114th Annual Meeting of the American Association for Cancer Research (AACR-2023)
- 09 Nov 2022 Celldex Therapeutics plans clinical trials for Solid tumours in patients with advanced malignancies in mid 2023