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4D 150

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Drug Profile

4D 150

Alternative Names: 4D-150

Latest Information Update: 17 Jan 2025

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At a glance

  • Originator 4D Molecular Therapeutics
  • Class Eye disorder therapies; Gene therapies; Small interfering RNA
  • Mechanism of Action Gene transference; Placenta growth factor inhibitors; RNA interference; Vascular endothelial growth factor A inhibitors; Vascular endothelial growth factor B inhibitors; Vascular endothelial growth factor C inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Diabetic macular oedema
  • Phase I/II Wet age-related macular degeneration
  • Preclinical Diabetic retinopathy

Most Recent Events

  • 17 Jan 2025 4D Molecular Therapeutics plans a pivotal phase-III 4FRONT-2 trial for Wet age-related macular degeneration in USA (Intravitreous, Injection) in Q3 2025
  • 10 Jan 2025 4D Molecular Therapeutics announces intention to submit the BLA to for Diabetic macular oedema
  • 10 Jan 2025 4D Molecular Therapeutics announces intention to submit the BLA to for Wet age-related macular degeneration

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