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ARO PNPLA3

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Drug Profile

ARO PNPLA3

Alternative Names: ARO-JNJ1; ARO-PNPLA3; JNJ-0795; JNJ-75220795

Latest Information Update: 28 May 2024

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At a glance

  • Originator Arrowhead Pharmaceuticals
  • Developer Arrowhead Pharmaceuticals; Johnson & Johnson Innovative Medicine
  • Class Hepatoprotectants; Small interfering RNA
  • Mechanism of Action Adiponutrin expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Fatty liver; Non-alcoholic steatohepatitis

Most Recent Events

  • 28 May 2024 No recent reports of development identified for phase-I development in Fatty liver in USA (SC, Injection)
  • 01 Oct 2023 Janssen Pharmaceuticals is now called Johnson & Johnson Innovative Medicine (Janssen Pharmaceuticals website, October 2023)
  • 31 Mar 2023 Janssen Research & Development completes a phase I trial in Fatty liver disease in USA (SC) (NCT04844450)

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