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AVB 114

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Drug Profile

AVB 114

Alternative Names: Autologous mesenchymal stromal cell coated fistula plug - Avobis Bio; AVB-114; MSC-AFP

Latest Information Update: 25 Jul 2024

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At a glance

  • Originator Mayo Clinic; W. L. Gore & Associates
  • Developer Avobis Bio; Mayo Clinic
  • Class Mesenchymal stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Rectal fistula

Most Recent Events

  • 19 Jul 2024 Avobis Bio initiates an EAP-STOMP2 expanded-access programme for Rectal fistula in USA (Parenteral) (NCT06509828)
  • 28 Dec 2022 No recent reports of development identified for phase-I development in Rectal-fistula(In adolescents, In children, Treatment-experienced) in USA (Parenteral)
  • 01 Dec 2021 Phase-II clinical trials in Rectal fistula (Treatment-experienced) in USA (Parenteral) (NCT04847739)

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