Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

AVB 114

Next Previous
Drug Profile

AVB 114

Alternative Names: Autologous mesenchymal stromal cell coated fistula plug - Avobis Bio; AVB-114; MSC-AFP

Latest Information Update: 10 Mar 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Mayo Clinic; W. L. Gore & Associates
  • Developer Avobis Bio; Mayo Clinic
  • Class Mesenchymal stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Rectal fistula

Most Recent Events

  • 27 Feb 2025 AVB 114 receives Fast Track designation for Rectal fistula [Parenteral] (Treatment-experienced) in USA
  • 27 Feb 2025 AVB 114 receives IND clearance from the US FDA for Crohn's perianal fistulas in USA, prior to February 2025
  • 27 Feb 2025 Avobis Bio completes enrolment in a phase II trial in Rectal fistula (Treatment-experienced) in USA (Parenteral), prior to February 2025 (NCT04847739)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top