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MPT 0118

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Drug Profile

MPT 0118

Alternative Names: MPT-0118

Latest Information Update: 28 May 2024

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At a glance

  • Originator Helmholtz Zentrum Munchen
  • Developer Helmholtz Zentrum Munchen; Monopteros Therapeutics
  • Class Antineoplastics; Phenothiazines; Small molecules
  • Mechanism of Action MALT1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II B-cell lymphoma; Brain metastases; Ovarian cancer; Solid tumours

Most Recent Events

  • 28 May 2024 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (PO, Tablet)
  • 20 Oct 2023 Safety, efficacy and pharmacokinetics data from a phase I/Ib trial in Solid tumours presented at the 48th European Society for Medical Oncology Congress (ESMO-2023)
  • 06 Oct 2022 Phase-I/II clinical trials in B-cell lymphoma (Monotherapy) in USA (unspecified route) (Monopteros therapeutics pipeline oct 2022)

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