Suzetrigine - Vertex Pharmaceuticals
Alternative Names: JOURNAVX; VX-548Latest Information Update: 21 May 2025
At a glance
- Originator Vertex Pharmaceuticals
- Class 1 ring heterocyclic compounds; Amides; Analgesics; Ethers; Fluorinated hydrocarbons; Fluorobenzenes; Non-opioid analgesics; Pyridines; Small molecules
- Mechanism of Action Nav1.8 voltage-gated sodium channel inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Acute pain
- Phase III Neuropathic pain
- Phase I Pain
Most Recent Events
- 14 May 2025 Latigo Biotherapeutics plans a phase I trial for Pain in New Zealand (NCT06972212)
- 29 Apr 2025 Vertex Pharmaceuticals completes a phase I pharmacokinetics trial in the US (PO) (NCT06820307)
- 24 Apr 2025 Vertex Pharmaceuticals completes a phase I trial in Pain (In volunteers) in the US (PO) (NCT06834009)