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Suzetrigine - Vertex Pharmaceuticals

Drug Profile

Suzetrigine - Vertex Pharmaceuticals

Alternative Names: VX-548

Latest Information Update: 22 Apr 2024

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At a glance

  • Originator Vertex Pharmaceuticals
  • Class 1 ring heterocyclic compounds; Amides; Analgesics; Ethers; Fluorinated hydrocarbons; Fluorobenzenes; Pyridines; Small molecules
  • Mechanism of Action Nav1.8 voltage-gated sodium channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Acute pain
  • Phase II Neuropathic pain; Radiculopathy
  • Phase I Pain

Most Recent Events

  • 18 Apr 2024 Vertex Pharmaceuticals announces intention to complete the submit of rolling NDA to the US FDA for Acute pain by the second quarter of 2024
  • 18 Apr 2024 Vertex Pharmaceuticals plans two pivotal phase III trials for diabetic peripheral neuropathy in second half of 2024
  • 02 Apr 2024 Vertex Pharmaceuticals plans a phase I trial in Pain (PO) (NCT06336096)
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