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SLN 501

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Drug Profile

SLN 501

Alternative Names: SLN-501

Latest Information Update: 29 Mar 2024

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At a glance

  • Originator Silence Therapeutics
  • Developer Mallinckrodt Inc.; Silence Therapeutics
  • Class Small interfering RNA
  • Mechanism of Action Complement C3 expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Immunological disorders

Most Recent Events

  • 13 Mar 2024 Silence Therpaeutics completes a phase I trial in Immunological disorders in USA (Parenteral)
  • 02 Sep 2022 Phase-I clinical trials in Immunological disorders in USA (Parenteral) (Mallinckrodt pipeline, September 2022)
  • 23 Mar 2022 Silence Therapeutics and Mallinckrodt files a clinical trial application (CTA) to initiate a phase I trial for Immunological disorders
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