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Rexaceract

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Drug Profile

Rexaceract

Alternative Names: GT-02287

Latest Information Update: 03 Jul 2026

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At a glance

  • Originator Gain Therapeutics
  • Class Antidementias; Antineoplastics; Antiparkinsonians; Neuroprotectants; Pharmacological chaperones; Small molecules
  • Mechanism of Action Galactosylceramidase modulators; Glucosylceramidase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Parkinson's disease
  • Preclinical Alzheimer's disease; Gaucher's disease
  • Research Dementia
  • Discontinued Alpha 1-antitrypsin deficiency; Globoid cell leukodystrophy; GM1 gangliosidosis; Solid tumours

Most Recent Events

  • 01 Jul 2026 US FDA approves IND application for T 02287 in Parkinson’s disease
  • 30 Jun 2026 Gain Therapeutics plans a phase IIa trial for Parkinson's disease in US, Australia and Europe in third quarter of 2026
  • 26 May 2026 Efficacy data from a phase Ib trial in Parkinson's disease released by Gain Therapeutics

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