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Cirtociclib - Blueprint Medicines

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Drug Profile

Cirtociclib - Blueprint Medicines

Alternative Names: BLU-222

Latest Information Update: 28 Apr 2026

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At a glance

  • Originator Blueprint Medicines
  • Class 1 ring heterocyclic compounds; 2 ring heterocyclic compounds; Amines; Antineoplastics; Ethers; Fluorocarbons; Pyrazines; Pyrazoles; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase I/II HER2 negative breast cancer; Solid tumours
  • No development reported Cancer; Gynaecological cancer; Ovarian cancer

Most Recent Events

  • 28 Apr 2026 No recent reports of development identified for preclinical development in Ovarian-cancer in USA
  • 09 Feb 2026 (NCT05252416) - Kdm, intro dev lines added and HE added
  • 28 Jan 2026 No recent reports of development identified for preclinical development in Gynaecological-cancer in USA

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