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BLU 222

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Drug Profile

BLU 222

Alternative Names: BLU-222

Latest Information Update: 28 May 2025

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At a glance

  • Originator Blueprint Medicines
  • Class 1 ring heterocyclic compounds; 2 ring heterocyclic compounds; Amines; Antineoplastics; Ethers; Fluorocarbons; Pyrazines; Pyrazoles; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase I/II HER2 negative breast cancer; Solid tumours
  • Preclinical Gynaecological cancer; Ovarian cancer
  • No development reported Cancer

Most Recent Events

  • 28 May 2025 No recent reports of development identified for preclinical development in Cancer in USA
  • 25 Apr 2025 Pharmacodynamics and adverse evenst data from a preclinical trial in Small cell lung cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 02 Jul 2024 Chemical structure information added

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