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ALM 27134

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Drug Profile

ALM 27134

Alternative Names: ALM-27134; Anti-human IL1RAP antagonist mAb; Anti-IL-1RAP mAb - Almirall S.A; ISB-880

Latest Information Update: 25 Aug 2025

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At a glance

  • Originator Ichnos Sciences
  • Developer Almirall S.A.
  • Class Anti-inflammatories; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Interleukin-1 receptor accessory protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Autoimmune disorders; Hidradenitis suppurativa

Most Recent Events

  • 25 Jul 2025 Almirall completes a phase I trial in Hidradenitis suppurativa (In volunteers) (Parenteral)
  • 25 Jul 2025 Adverse events data from a phase I trial in Hidradenitis suppurativa released by Almirall
  • 24 Feb 2025 Phase-I clinical trials in Hidradenitis suppurativa (In volunteers) (Parenteral) before February 2025

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