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GNSC 001

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Drug Profile

GNSC 001

Alternative Names: AAVIL-1Ra; GNSC-001; IL-1Ra; Sc-rAAV2.5IL-1Ra

Latest Information Update: 31 Oct 2023

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At a glance

  • Originator Mayo Clinic
  • Class Antirheumatics; Gene therapies
  • Mechanism of Action Gene transference; Interleukin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Osteoarthritis

Most Recent Events

  • 24 Oct 2023 Efficacy, adverse events and pharmacodynamics from a phase I trial in Osteoarthritis released by Genascence Corporation
  • 12 Jun 2023 Genascence Corporation initiates enrolment in a phase I DONATELLO trial for Osteoarthritis (In adults, In the elderly) in USA (Intra-articular, Injection) (NCT05835895)
  • 23 Feb 2023 Phase-I development in Osteoarthritis is ongoing USA

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