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KD 496

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Drug Profile

KD 496

Alternative Names: KD-496; KD-4964th

Latest Information Update: 24 Aug 2026

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At a glance

  • Originator Nanjing KAEDI Biotech
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Gastric cancer; Pancreatic cancer

Most Recent Events

  • 02 Jun 2026 Efficacy and adverse events data from phase-I clinical trials in Pancreatic cancer and Gastric cancer presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
  • 17 Oct 2025 Efficacy and adverse events data from phase-I clinical trials in Pancreatic cancer and Gastric cancer presented at the 50th European Society for Medical Oncology Congress (ESMO-2025)
  • 18 Nov 2023 Peking University and KAEDI plans a phase I trial for Solid tumors (In adults, In the elderly, Late-stage disease, Second-line therapy or greater) in China (Parenteral, Infusion) (NCT06134960)

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