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SMART 101

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Drug Profile

SMART 101

Alternative Names: ProTcells™ (CD7+/CD34-; CD5- cells); ProTcell™; SMART-101

Latest Information Update: 21 Dec 2023

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At a glance

  • Originator Smart Immune
  • Class Antineoplastics; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Severe combined immunodeficiency; Precursor B-cell lymphoblastic leukaemia-lymphoma; Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Haematological malignancies; Myelodysplastic syndromes; Precursor B-cell lymphoblastic leukaemia-lymphoma; Severe combined immunodeficiency
  • Clinical Phase Unknown Unspecified

Most Recent Events

  • 16 Oct 2023 Phase-I/II clinical trials in Myelodysplastic syndromes in France (Parenteral) (NCT05768035)
  • 28 Jun 2023 Preclinical trials in Acute myeloid leukaemia in France (Parenteral) (Smart Immune pipeline, June 2023)
  • 28 Jun 2023 Preclinical trials in Myelodysplastic syndromes in France (Parenteral) (Smart Immune pipeline, June 2023)

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