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Research programme: proteasome inhibitors - QLi5 Therapeutics

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Drug Profile

Research programme: proteasome inhibitors - QLi5 Therapeutics

Latest Information Update: 11 Dec 2025

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At a glance

  • Originator The Lead Discovery Center
  • Developer QLi5 Therapeutics
  • Class Anti-inflammatories; Antineoplastics; Small molecules
  • Mechanism of Action Proteasome inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Cancer
  • Discontinued Inflammation

Most Recent Events

  • 11 Dec 2025 QLi5 Therapeutics has patent protection for "Macrocyclic compounds as proteasome subunit beta type-5 inhibitors" in the European Union and has patent pending applications in Denmark, Japan, Canada, China, the US, Australia, Italy, South Africa
  • 10 Dec 2025 Discontinued for Inflammation in Germany (unspecified route) (QLi5 Therapeutics pipeline, December 2025)
  • 10 Dec 2025 Preclinical trials in Autoimmune disorders in Germany (unspecified route)

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