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Anti PD L1 immune stimulating antibody conjugate - Bolt Biotherapeutics

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Drug Profile

Anti PD L1 immune stimulating antibody conjugate - Bolt Biotherapeutics

Alternative Names: Anti-PD-L1 ISAC; PD-L1 Boltbody™ ISAC; PD-L1-ISAC

Latest Information Update: 04 Apr 2026

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At a glance

  • Originator Bolt Biotherapeutics
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action Myeloid cell stimulants; T lymphocyte stimulants; Toll-like receptor 7 agonists; Toll-like receptor 8 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Suspended Breast cancer; Head and neck cancer; Non-small cell lung cancer

Most Recent Events

  • 12 Mar 2026 Bolt Therapeutics plans to initiate clinical trials within 18 months of development resumption
  • 12 Mar 2026 Anti PD L1 immune stimulating antibody conjugate - Bolt Biotherapeutics is available for licensing as of 12 Mar 2026. www.boltbio.com
  • 12 Mar 2026 Suspended - Preclinical for Breast cancer in USA (Parenteral) as Bolt Therapeutics seeks partnership or funding

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