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Clofutriben - Sparrow pharmaceuticals

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Drug Profile

Clofutriben - Sparrow pharmaceuticals

Alternative Names: SPI-62

Latest Information Update: 18 Nov 2025

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At a glance

  • Originator Sparrow Pharmaceuticals
  • Class Antihyperglycaemics; Antirheumatics; Obesity therapies; Small molecules
  • Mechanism of Action 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cushing syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adrenal gland disorders; Cushing syndrome; Polymyalgia rheumatica; Type 2 diabetes mellitus
  • No development reported Diabetic neuropathies; Obesity

Most Recent Events

  • 13 Nov 2025 Sparrow Pharmaceuticals plans a phase I pharmacokinetics trial (In adults, In the elderly) in the US, in November 2025 (PO) (NCT07227922)
  • 03 Oct 2025 Sparrow Pharmaceuticals initiates a phase I drug-drug interaction trial (In volunteers) in USA (PO) (NCT07226635)
  • 24 Sep 2025 Phase-II clinical trials in Type 2 diabetes mellitus (Treatment-resistant) (PO), prior to September 2025

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