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Clofutriben - Sparrow pharmaceuticals

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Drug Profile

Clofutriben - Sparrow pharmaceuticals

Alternative Names: SPI-62

Latest Information Update: 29 Sep 2025

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At a glance

  • Originator Sparrow Pharmaceuticals
  • Class Antihyperglycaemics; Antirheumatics; Obesity therapies; Small molecules
  • Mechanism of Action 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cushing syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adrenal gland disorders; Cushing syndrome; Polymyalgia rheumatica; Type 2 diabetes mellitus
  • No development reported Diabetic neuropathies; Obesity

Most Recent Events

  • 24 Sep 2025 Phase-II clinical trials in Type 2 diabetes mellitus (Treatment-resistant) (PO), prior to September 2025
  • 04 Sep 2025 Chemical structure information added.
  • 12 Jul 2025 Efficacy and adverse event data from the phase II RESCUE trial in Cushing syndrome presented at the 107th Annual Meeting of the Endocrine Society (ENDO-2025)

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