Clofutriben - Sparrow pharmaceuticals
Alternative Names: SPI-62Latest Information Update: 26 May 2025
At a glance
- Originator Sparrow Pharmaceuticals
- Class Antirheumatics; Obesity therapies; Small molecules
- Mechanism of Action 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Adrenal gland disorders; Cushing syndrome; Polymyalgia rheumatica
- No development reported Diabetic neuropathies; Obesity
Most Recent Events
- 16 May 2025 Sparrow Pharmaceuticals terminates a phase I trial for Polymyalgia Rheumatica (Combination therapy) in Germany due to lack of enrollment (NCT06281236)
- 25 Apr 2025 Sparrow Pharmaceuticals completes a phase-II clinical trials in Polymyalgia rheumatica (Combination therapy) in Germany and Poland (PO) (NCT05436652) (EudraCT2022-000299-20)
- 26 Feb 2025 Sparrow Pharmaceuticals terminates a phase II ACSPIRE trial for Cushing syndrome due to unclear benefit for this patient population in USA, Romania and United Kingdom (NCT05436639)