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PF 08046052

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Drug Profile

PF 08046052

Alternative Names: LAVA-1223; PF-08046052; SGN-EGFRd 2

Latest Information Update: 15 Jun 2024

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At a glance

  • Originator VU University Medical Center
  • Developer Seagen
  • Class Antineoplastics; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 05 Apr 2024 Pharmacodynamics data from a preclinical trial in Colorectal cancer presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 14 Dec 2023 Seagen has been acquired by Pfizer
  • 08 Nov 2023 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT05983133)

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