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GS 1427

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Drug Profile

GS 1427

Alternative Names: GS-1427; α4β7 inhibitor - Gilead Sciences

Latest Information Update: 20 Jan 2025

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At a glance

  • Originator Gilead Sciences
  • Class Anti-inflammatories
  • Mechanism of Action Alpha4beta7 integrin antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ulcerative colitis
  • No development reported Inflammatory bowel diseases

Most Recent Events

  • 08 Sep 2024 Pharmacokinetics and adverse event data from the phase I trial in Inflammatory bowel diseases presented at the 2024 American College of Clinical Pharmacology Annual Meeting (ACCP-2024)
  • 28 Jul 2024 No recent reports of development identified for phase-I development in Inflammatory-bowel-diseases(In volunteers) in Australia (PO, Capsule)
  • 27 Mar 2024 Phase-II clinical trials in Ulcerative colitis (In adults, In the elderly, Combination therapy) in USA (PO) (NCT06290934)

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