M 4645
Alternative Names: M-4645Latest Information Update: 28 May 2025
At a glance
- Originator Merck KGaA
- Class Antineoplastics; Indazoles
- Mechanism of Action Proto-oncogene protein c-kit inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- No development reported Gastrointestinal stromal tumours
Most Recent Events
- 28 May 2025 No recent reports of development identified for preclinical development in Gastrointestinal-stromal-tumours in Germany
- 10 Apr 2021 Preclinical trials in Gastrointestinal stromal tumours in Germany (unspecified route), prior to April 2021
- 10 Apr 2021 Pharmacodynamics data from preclinical trials in Gastrointestinal stromal tumours presented at the 112th Annual Meeting of the American Association for Cancer Research (AACR-2021)