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Delpacibart zotadirsen - Avidity Biosciences

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Drug Profile

Delpacibart zotadirsen - Avidity Biosciences

Alternative Names: AOC-1044; del-zota

Latest Information Update: 19 Aug 2024

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At a glance

  • Originator Avidity Biosciences
  • Class Drug conjugates; Immunoconjugates; Monoclonal antibodies; Oligonucleotides; Small interfering RNA
  • Mechanism of Action Dystrophin expression stimulants; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Duchenne muscular dystrophy

Most Recent Events

  • 09 Aug 2024 Efficacy and adverse events data from phase I/II EXPLORE44™trial in Duchenne muscular dystrophy released by Avidity Biosciences
  • 09 Aug 2024 Avidity Biosciences completes enrollment in the phase I/II EXPLORE44™ trial in Duchenne muscular dystrophy (In adults, In children, In adolescents) (IV)
  • 20 Feb 2024 US FDA grants Rare Pediatric Disease Designation (RPDD) to AOC 1044 for the treatment of Duchenne muscular dystrophy in USA

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