Drug Profile

PALI 2108

Alternative Names: GT-2108; PALI-2108

Latest Information Update: 01 Mar 2026

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At a glance

Originator Giiant Pharma
Developer Giiant Pharma; Palisade Bio
Class Anti-inflammatories; Antifibrotics; Small molecules
Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Crohn's disease
Phase I Ulcerative colitis
Preclinical Inflammatory bowel diseases

Most Recent Events

23 Feb 2026 Pharmacodynamic and adverse even data from a phase Ib trial in Ulcerative colitis released by Palisade Bio
07 Jan 2026 Palisade Bio plans to submit IND application to the USFDA for phase II trial in ulcerative colitis in 2026
07 Jan 2026 Palisade Bio plans a phase-II trial for Ulcerative colitis in USA (PO)

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