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PALI 2108

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Drug Profile

PALI 2108

Alternative Names: GT-2108; PALI-2108

Latest Information Update: 19 Sep 2025

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At a glance

  • Originator Giiant Pharma
  • Developer Giiant Pharma; Palisade Bio
  • Class Anti-inflammatories; Antifibrotics; Small molecules
  • Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Ulcerative colitis
  • Preclinical Crohn's disease; Inflammatory bowel diseases

Most Recent Events

  • 17 Sep 2025 Updated efficacy, pharmacokinetics and adverse events data from a phase I trial in Ulcerative colitis released by Palisade Bio
  • 08 Sep 2025 Palisade Bio received IND clearance from health Canada for the initiation of phase Ib trial in Fibrostenotic Crohn’s Disease
  • 08 Sep 2025 Palisade Bio plans to initiate a phase Ib trial for Fibrostenotic Crohn’s Disease

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