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DFF 332

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Drug Profile

DFF 332

Alternative Names: DFF-332

Latest Information Update: 16 Jul 2024

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At a glance

  • Originator Novartis Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Endothelial PAS domain-containing protein 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Renal cell carcinoma

Most Recent Events

  • 31 May 2024 Pharmacokinetics, efficacy and adverse events data from a phase I/Ib trial in Renal cell carcinoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 30 Nov 2021 Phase-I clinical trials in Renal cell carcinoma (Late-stage disease, Metastatic disease, Second-line therapy or greater, Monotherapy, Inoperable/Unresectable) in Italy, France, Singapore, USA (PO) (NCT04895748)
  • 20 Nov 2021 Phase-I clinical trials in Renal cell carcinoma (Late-stage disease, Metastatic disease, Second-line therapy or greater, Inoperable/Unresectable, Combination therapy) in Italy, France, Singapore, USA (PO)

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