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Pasritamig - Janssen Research & Development

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Drug Profile

Pasritamig - Janssen Research & Development

Alternative Names: JNJ-78278343; JNJ-8343

Latest Information Update: 15 Sep 2025

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At a glance

  • Originator Janssen Research & Development; Zymeworks
  • Developer Janssen Research & Development
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Prostate cancer

Most Recent Events

  • 10 Sep 2025 Janssen Research & Development plans a phase III trial for Prostate Cancer (Hormone refractory, Late-stage disease, Metastatic disease, Second-line therapy or greater) in the USA, Australia and Puerto Rico (IV, Infusion) in September 2025 (NCT07164443)
  • 18 Jul 2025 Pasritamig is still in phase I trial for Prostate-cancer in Prostate-cancer (Hormone refractory, Late-stage disease, Metastatic disease, Second-line therapy or greater) in France, Spain, Netherlands, USA (SC) (NCT04898634)
  • 15 Jul 2025 Janssen Research & Development plans phase-I trial for Adenocarcinoma (Combination therapy, Metastatic disease, Hormone-refractory) in USA (IV), (NCT07082920)

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