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TBS 2025

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Drug Profile

TBS 2025

Alternative Names: KVA-001; KVA-002; KVA-12.1; KVA-12123; TBS-2025

Latest Information Update: 03 Jul 2025

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At a glance

  • Originator GigaGen
  • Developer TuHURA Biosciences
  • Class Antibodies; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants; VISTA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Preclinical Acute myeloid leukaemia; Colorectal cancer; Non-small cell lung cancer

Most Recent Events

  • 30 Jun 2025 Kineta has been acquired and merged into TuHURA Biosciences
  • 30 Jun 2025 TuHURA Biosciences plans a phase IIa/b trial for Acute myeloid leukemia (Combination therapy) in the second half of 2025
  • 25 Apr 2025 Efficacy, adverse events and pharmacokinetic data from a phase I/II trial in Solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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