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KVA 12123

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Drug Profile

KVA 12123

Alternative Names: KVA-001; KVA-002; KVA-12.1; KVA-12123

Latest Information Update: 09 Jan 2025

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At a glance

  • Originator GigaGen
  • Developer Kineta
  • Class Antibodies; Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants; VISTA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours
  • Preclinical Acute myeloid leukaemia; Colorectal cancer; Non-small cell lung cancer

Most Recent Events

  • 09 Jan 2025 TuHURA Biosciences plans a phase IIa/b trial for Acute myeloid leukemia in 2025
  • 12 Dec 2024 TuHURA Biosciences enters into definitive merger agreement to acquire Kineta including the rights to KVA12123
  • 08 Nov 2024 Updated adverse event data from the phase I/II VISTA-101 trial in Solid tumours released by Kineta

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