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Ori CAR 001

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Drug Profile

Ori CAR 001

Alternative Names: Anti-GPC3 CAR-T cell therapy - OriginCell Therapeutics; G3-CAR-Ori2; Ori-C101; Ori-CAR-001; OriC101 - OriCell Therapeutics

Latest Information Update: 02 Jan 2023

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At a glance

  • Originator OriginCell Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Liver cancer

Most Recent Events

  • 15 Dec 2022 Phase-I/II clinical trials in Liver cancer (Late-stage disease, Second-line therapy or greater, Inoperable/Unresectable) in China (IV) (NCT05652920)
  • 21 Sep 2022 The National Medical Products Administration (NMPA) approved the Investigational New Drug (IND) submission for Ori C101 for the treatment of Liver cancer
  • 06 Jun 2021 Preliminary efficacy and adverse events data from phase I trial in Liver cancer released by OriginCell Therapeutics

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