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IPH 65

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Drug Profile

IPH 65

Alternative Names: CD20-NKCE-IL2v; IPH-65; IPH-6501; Tetra-specific ANKET; Tetra-specific NK cell engaging antibody - Innate Pharma

Latest Information Update: 20 Jun 2025

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At a glance

  • Originator Innate Pharma
  • Class Antibodies; Antineoplastics; Immunotherapies; Interleukins; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Interleukin 2 replacements; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase I/II Non-Hodgkin's lymphoma

Most Recent Events

  • 13 Jun 2025 Pharmacodynamics data from the preclinical trial in Non-Hodgkin's lymphoma released by Innate Pharma
  • 13 Jun 2024 Pharmacodynamics data from a preclinical trial in Non-Hodgkin's lymphoma presented at the 29th Congress of the European Haematology Association (EHA-2024)
  • 12 Jun 2024 Phase-I/II clinical trials in Non-Hodgkin's lymphoma (Late-stage disease, Second-line therapy or greater) in France (Parenteral) (NCT06088654)

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