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Aflibercept biosimilar - Clover Biopharmaceuticals

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Drug Profile

Aflibercept biosimilar - Clover Biopharmaceuticals

Alternative Names: SCB 420

Latest Information Update: 28 Jul 2025

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At a glance

  • Originator Clover Biopharmaceuticals
  • Class Antineoplastics; Eye disorder therapies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Recombinant fusion proteins
  • Mechanism of Action Placenta growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Wet age-related macular degeneration

Most Recent Events

  • 28 Jul 2025 No recent reports of development identified for preclinical development in Wet age-related macular degeneration in China (Intravitreous, Injection)
  • 19 Apr 2022 Clover Biopharmaceuticals withdraws a phase I trial in Wet-age related macular degeneration (In adults, Treatment experienced, In the elderly) in Australia, New Zealand and China (Intravitreous) (NCT04919096)
  • 16 Jun 2021 Preclinical trials in Wet age-related macular degeneration in China (Intravitreous) before June 2021

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