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Cabotegravir stearate

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Drug Profile

Cabotegravir stearate

Alternative Names: Nanoformulated stearoylated CAB ester prodrug - Exavir Therapeutics; NM2CAB; XVIR-110; XVR 110

Latest Information Update: 23 Apr 2024

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At a glance

  • Originator University of Nebraska Medical Center
  • Developer Exavir Therapeutics; University of Nebraska Medical Center
  • Class Amides; Antiretrovirals; Esters; Fluorobenzenes; Oxazoles; Pyrazines; Pyridones; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical HIV infections

Most Recent Events

  • 03 Mar 2024 Pharmacokinetics and adverse events data from a preclinical pharmacokinetics study presented at the31st Conference on Retroviruses and Opportunistic Infections 2024 (CROI-2024)
  • 23 Aug 2023 Exavir Therapeutics plans to file an IND for XVIR 110
  • 09 Jun 2021 Preclinical trials in HIV infections (Prevention) in USA (IM) before June 2021

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