Drug Profile

Macupatide - Eli Lilly and Company

Alternative Names: LAGIPRA; LY 3532226

Latest Information Update: 27 Jan 2026

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At a glance

Originator Eli Lilly and Company
Class Antihyperglycaemics; Obesity therapies
Mechanism of Action Gastric inhibitory polypeptide receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Obesity; Type 2 diabetes mellitus
Phase I Type 1 diabetes mellitus

Most Recent Events

12 Dec 2025 Eli Lilly and Company completes a phase I trial in Obesity in the US and Singapore (SC) (NCT06557356)
16 Oct 2025 Phase-II clinical trials in Obesity (Combination therapy) in USA (SC) (NCT07215559)
16 Oct 2025 Phase-II clinical trials in Obesity (Monotherapy) in USA (SC) (NCT07215559)

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