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Brexanolone - Lipocine

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Drug Profile

Brexanolone - Lipocine

Alternative Names: LPCN-1154; LPCN-1154A

Latest Information Update: 03 Mar 2026

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At a glance

  • Originator Lipocine
  • Class Antidepressants; Antiepileptic drugs; Small molecules; Steroids
  • Mechanism of Action GABA A receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Postnatal depression

Highest Development Phases

  • Phase III Postnatal depression

Most Recent Events

  • 17 Feb 2026 Lipocine completes a phase III trial in Postnatal depression (In adolescents, In adults) in USA (PO, Tablet) (NCT06979544)
  • 20 Jan 2026 Lipocine completes enrolment in its phase-III trial in Postnatal depression in USA (In adolescents, In adults) (PO) (NCT06979544)
  • 12 Jan 2026 Updated adverse events data from a phase III trial in Postnatal depression released by Lipocine

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