Drug Profile

SPL23 ASO

Alternative Names: SPL23-2; SPL23-ASO

Latest Information Update: 28 Jul 2025

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At a glance

Originator SpliSense
Class Antifibrotics; Antisense oligonucleotides
Mechanism of Action Cystic fibrosis transmembrane conductance regulator expression modulators; RNA interference

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

28 Jul 2025 No recent reports of development identified for preclinical development in Cystic-fibrosis in Israel (Inhalation)
27 Jun 2023 SpliSense plans to file an IND application for Cystic fibrosis (SpliSense pipeline, June 2023)
11 Jun 2021 Preclinical trials in Cystic fibrosis in Israel (Inhalation)

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