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HMPL A83

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Drug Profile

HMPL A83

Alternative Names: HMPL-A83

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator HUTCHMED
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD47 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • No development reported Haematological malignancies

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for preclinical development in Haematological-malignancies in Hong Kong (IV, Injection)
  • 07 Apr 2025 Hutchmed completes a phase I trials in Solid tumours (Late-stage disease, Metastatic disease) in China (IV) (NCT05429008)
  • 31 Dec 2022 HUTCHMED has patents pending for HMPL 283 in China, USA, Europe, Japan, Argentina and Taiwan

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