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ZF 887

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Drug Profile

ZF 887

Alternative Names: ZF-887

Latest Information Update: 26 Jun 2026

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At a glance

  • Originator Z Factor Limited
  • Developer Centessa Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Alpha 1-antitrypsin modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alpha 1-antitrypsin deficiency

Most Recent Events

  • 24 Jun 2026 Centessa Pharmaceuticals has been acquired by Eli Lilly and Company
  • 04 Apr 2022 Discontinued - Preclinical for Alpha 1-antitrypsin deficiency in United Kingdom (PO) (Centessa pipeline, April 2022)
  • 01 Jul 2021 Preclinical trials in Alpha 1-antitrypsin deficiency in United Kingdom (PO) (Centessa Pharmaceuticals' pipeline, July 2021)

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