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SAR 445514

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Drug Profile

SAR 445514

Alternative Names: IPH-64; IPH-6401; SAR-445514; SAR’514

Latest Information Update: 09 Jan 2026

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At a glance

  • Originator Innate Pharma
  • Developer Innate Pharma; Sanofi
  • Class Antineoplastics; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Amyloid light-chain amyloidosis; Immunological disorders; Multiple myeloma

Most Recent Events

  • 09 Jan 2026 Pharmacodynamics data from a preclinical studies in Multiple myeloma presented at the 30th Congress of the European Haematology Association (EHA-2025)
  • 31 Dec 2025 Discontinued - Phase-I for Immunological disorders (Parenteral)
  • 09 Jun 2025 Sanofi terminates phase I/II clinical trials in Amyloid light-chain amyloidosis and multiple myeloma (Monotherapy, Second-line therapy or greater) in United Kingdom, Spain, Italy, Hungary, Czech Republic, Belgium (SC) based on sponsor decision not driven by any safety concerns (NCT05839626)

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