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MP 0533

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Drug Profile

MP 0533

Alternative Names: AML CD3 x CD33 x CD70 x CD123 ; MP-0533; Multi-specific DARPin® T-cell engager; Multi-specific T-cell engager - Molecular Partners AG

Latest Information Update: 24 Feb 2026

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At a glance

  • Originator Molecular Partners AG
  • Class Antineoplastics; Immunotherapies; Recombinant fusion proteins; Single-domain antibodies
  • Mechanism of Action T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 06 Dec 2025 Efficacy and adverse events data from a phase I/IIa trial in Acute myeloid leukemia (AML) or Myelodysplastic syndrome (MDS) presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-2025)
  • 12 Jun 2025 Efficacy, adverse events, pharmacokinetics and pharmacodynamics data from a phase I/IIa trial in Acute myeloid leukemia (AML) or Myelodysplastic syndrome (MDS) presented at the 30th Congress of the European Haematology Association, 2025 (EHA-2025)
  • 12 Jan 2025 Efficacy data from a phase I/IIa trial in Acute myeloid leukemia (AML) or Myelodysplastic syndrome (MDS) released by Molecular Partners

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