MP 0533
Alternative Names: AML CD3 x CD33 x CD70 x CD123 ; MP-0533; Multi-specific DARPin® T-cell engager; Multi-specific T-cell engager - Molecular Partners AGLatest Information Update: 09 Sep 2024
At a glance
- Originator Molecular Partners AG
- Class Antineoplastics; Immunotherapies; Recombinant fusion proteins; Single-domain antibodies
- Mechanism of Action T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes
Most Recent Events
- 29 Jul 2024 Efficacy data from a preclinical studies in Acute myeloid leukemia (AML) or Myelodysplastic syndrome (MDS) released by Molecular Partners
- 25 Dec 2023 Updated efficacy data from a phase I/IIa trial in acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) released by Molecular Partners
- 09 Dec 2023 Pharmacokinetics, efficacy, and adverse events data from the phase I/IIa trial in Acute myeloid leukemia or Myelodysplastic syndrome presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)