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CC 91633

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Drug Profile

CC 91633

Alternative Names: BMS-986397; CC-91633

Latest Information Update: 03 Oct 2025

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At a glance

  • Originator Celgene Corporation
  • Class Antineoplastics; Small molecules
  • Mechanism of Action CRBN protein modulators; Ubiquitin protein ligase complex modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 30 Jul 2025 Celgene terminates a phase-I trial in Myelodysplastic syndromes and Myelodysplastic syndromes in USA and Spain due to early positive results (NCT04951778)
  • 19 Feb 2025 BMS 986397 is still in phase I trials for Acute myeloid leukaemia (Second-line therapy or greater) and Myelodysplastic syndrome (Second-line therapy or greater) in USA (PO) (NCT04951778)
  • 28 Dec 2024 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Second-line therapy or greater) in USA (PO)

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