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Zapomeran - Arcturus Therapeutics

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Drug Profile

Zapomeran - Arcturus Therapeutics

Alternative Names: ARCT-154; Kostaive; Sa-mRNA vaccine - Arcturus Therapeutics; Self-amplifying mRNA vaccine - Arcturus Therapeutics; VBC-COV19-154

Latest Information Update: 17 Dec 2025

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At a glance

  • Originator Arcturus Therapeutics
  • Developer Arcturus Therapeutics; Meiji Seika Pharma; Vinbiocare Biotechnology
  • Class COVID-19 vaccines; RNA vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Marketed COVID 2019 infections

Most Recent Events

  • 17 Dec 2025 Phase-III clinical trials in COVID-2019 infections (In adolescents, Prevention) in Japan (IM), before December 2025 (Meiji Seika Pharma pipeline, December 2025)
  • 30 Sep 2025 Pharmacodynamics data from a preclinical trials in COVID 2019 infections released by Arcturus Therapeutics
  • 26 Sep 2025 Meiji Seika Pharma launch 2-dose lyophilized presentation of KOSTAIVE® in Japan (IM, Injection)

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