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Soficabtagene geleucel - Wugen

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Drug Profile

Soficabtagene geleucel - Wugen

Alternative Names: Allogenic CAR-T cell therapies - Wugen; Anti-CD7 Allogeneic CAR T Cells - Wugen; WU-CART-007

Latest Information Update: 09 Dec 2025

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At a glance

  • Originator WUGEN
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor T-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Precursor T-cell lymphoblastic leukaemia-lymphoma
  • Phase I/II Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase I Haematological malignancies

Most Recent Events

  • 05 Dec 2025 Pharmacokinetics, pharmacodynamics and adverse events data from a phase I/II trial in Precursor cell lymphoblastic leukaemia-lymphoma and Precursor T cell lymphoblastic leukaemia lymphoma released by WUGEN
  • 27 Aug 2025 Wugen plans to file Biologics License Application (BLA) for Precursor T-cell lymphoblastic leukaemia-lymphoma, Precursor cell lymphoblastic leukaemia-lymphoma in 2027
  • 31 Jan 2025 Phase-II clinical trials in Precursor T-cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater, In infants, In children, In adolescents, In adults, In the elderly) in USA (IV) (NCT06514794)

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