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Soficabtagene geleucel - Wugen

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Drug Profile

Soficabtagene geleucel - Wugen

Alternative Names: Allogenic CAR-T cell therapies - Wugen; Anti-CD7 Allogeneic CAR T Cells - Wugen; WU-007; WU-CART-007

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator WUGEN
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor T-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Precursor T-cell lymphoblastic leukaemia-lymphoma
  • Phase I/II Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase I Haematological malignancies

Most Recent Events

  • 21 Jan 2026 Soficabtagene geleucel - Wugen receives Breakthrough Therapy status for Precursor cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater) in USA
  • 21 Jan 2026 Soficabtagene geleucel - Wugen receives Breakthrough Therapy status for Precursor T-cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater) in USA
  • 06 Dec 2025 Updated adverse events, pharmacodynamics, pharmacokinetics and efficacy data from a phase-I/II trial in Precursor T-cell lymphoblastic leukaemia-lymphoma presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2025)

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