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ARD 101

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Drug Profile

ARD 101

Alternative Names: ARD-101; Denatonium acetate monohydrate

Latest Information Update: 13 Nov 2025

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At a glance

  • Originator Aardvark Therapeutics
  • Class Anti-inflammatories; Obesity therapies; Small molecules
  • Mechanism of Action G protein-coupled receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Prader-Willi syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Prader-Willi syndrome
  • Phase I Obesity
  • Discontinued Weight gain

Most Recent Events

  • 04 Nov 2025 Efficacy and adverse event data from phase II trial in Obesity released by Aardvark Therapeutics
  • 01 Jul 2025 Phase-III clinical trials in Prader-Willi syndrome (In children, In adolescents, In adults, In the elderly) in Australia (PO) (NCT07197034)
  • 14 May 2025 Phase-I clinical trials in Obesity (PO) (Aardvark Therapeutics pipeline; May 2025)

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