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ENX 102

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Drug Profile

ENX 102

Alternative Names: ENX-102

Latest Information Update: 03 Oct 2025

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At a glance

  • Originator Engrail Therapeutics
  • Class Anxiolytics
  • Mechanism of Action GABA A alpha 2 receptor modulators; GABA A alpha 3 receptor modulators; GABA A alpha 5 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Anxiety disorders; Social phobia

Most Recent Events

  • 05 Sep 2025 Phase-II clinical trials in Social phobia in USA (PO) (NCT07193563)
  • 23 Jun 2025 Engrail Therapeutics completes a phase II trial in Anxiety disorders in United Kingdom (PO) (NCT06653296)
  • 09 Dec 2024 Phase-II clinical trials in Anxiety disorders in United Kingdom (PO) (NCT06653296)

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