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XmAb 808

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Drug Profile

XmAb 808

Alternative Names: B7-H3 x CD28 - Xencor; XmAb-808

Latest Information Update: 23 Feb 2026

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At a glance

  • Originator Xencor
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 23 Feb 2026 Phase I development is ongoing in USA (IV) (Xencor pipeline, February 2026)
  • 23 Feb 2026 Xencor plans a clinical trial for Solid tumours (Combination therapy) (Xencor pipeline, February 2026).
  • 28 Dec 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV)

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